Analgesic drug to prevent post surgery neuropathic pain

ERADICATE NEUROPATHIC PAIN WITH EXPECTED REDUCED SIDE-EFFECT.

Neuropathic pain induced by surgical interventions is a major public health problem because available treatments display sideeffects and weak efficiency.

Our research team has developed a new asset that consist in :

1 | Repurposing of Memantine, an antagonist of NMDA (N-Methyl-D-Aspartate) receptors usually prescribed for Alzheimer’s disease to prevent neuropathic pain following surgical interventions like mastectomy.

2 | Reduction of analgesics consumption and improvement of emotional state

Competitive Advantages

● Response to unmet therapeutic need

● Attractive to speed up drug development

● Contribute to life quality improvement

● Preventive analgesic effects

● Non-opioid

Development Status

● Clinical POC validated in a randomized clinical trial on 40 women undergoing mastectomy.

Compared with placebo, patients receiving Memantine showed a

significant reduction in post-mastectomy pain intensity, reduced use of

analgesic at 3 months and an improved emotional state.

Business Opportunities

● Chronic pain treatment