Anticoagulant from red algae

Context

Mimics from natural glycosaminoglycans are searched for their biological activities (anticoagulant, anti-inflammatory, antiparasitic, antiviral ...) and their potential applications (anticoagulant, anti-tumoural, cellular regeneration …). The most common is heparin use for regulate coagulation. Heparin currently used is isolated from pig bowels or beef lungs. Animal origin of these molecules is an issue in terms of its human use and the high production costs. Analogs of glycosaminoglycans with a natural origin may overcome such shortcomings and are highly sought after.

Technology

Polysaccharide extracted from a red algae with heparin-like in vitro anticoagulant properties. Structure homology of galactan sulfates extracted with the glycosaminoglycans present in conjunctive human tissues allows these molecules to mimic some biological activities (anticoagulant, anti-inflammatory, antiparasitic, antiviral ...) and to be potential candidates for healthcare applications.

Advantages / Benefits

● Marine origin natural resource
● Solved chemical structure
● In vitro anticoagulant activity comparable to heparin
● Established extraction and characterisation processes