AUTOMATIC SCORING OF LUNG DAMAGE

Cystic fibrosis is the most common inherited genetic disease in the Caucasian population (1/4500). Respiratory involvement is one of the main causes of death. Patients are monitored using clinical and functional markers and chest scans. But these follow-ups take a long time and are too variable. The method developed allows automatic scoring of pulmonary involvement in cystic fibrosis by CT scan. This score is well correlated with respiratory function, which was verified in two independent cohorts of patients.

Applications:

• Use in clinical practice for scoring chest scanners
• Use as a morphological marker in clinical studies
• Application to other chronic pulmonary diseases with similar CT manifestations

Competitive advantages:

• Automatic
• Quickness of execution
• Reproductibililty

Keywords: CT quantification, Automatic scoring, Cystic fibrosis, Lung segmentation, Histogram analysis