GIFT: New improved platelet lysates for: Neuroprotection, neurorestoration and neurogenesis

SATT NORD



23 Novembre 2016

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Fields

Biology / Medical

Sectors

Health

Platelets constitute abundant, natural, readily accessible sources of physiological mixtures of numerous growth factors (GFs) with proven effects on cell survival and proliferation.

Platelet lysates (PL) are already used in several fields of human regenerative medicine as well as for cell therapy procedures.

In particular, PLs contain a physiological balance of neurotrophic GFs thought to regulate the development, maintenance, function and plasticity of the vertebrate nervous system.

Improved PLs produced in the laboratory can potentially be used as disease-modifying strategy for the treatment of neurodegenerative disorders.

Benefits:

  • Improved PLs are more active than classical PL or single GF
  • Less toxic at high dosage than classical PL
  • Neuroprotection
  • Efficient on an in-vivo model of Parkinson’s diease
  • Platelets abundance
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