HAMLET-TEST

Behavior testing device designed to evaluate the topographical memory of mice in complex environments. The device automatically collects numerous types of information (movement, ingestion of food, water intake, physical activity, etc.) and is based on habituating the animal to a complex and enhanced environment.

Context
Finalized medical research depends both on the relevance of a given disease’s animal models and approach methods, notably in vivo and behavioral approaches. There are no “absolute” behavioral tests that specifically and selectively measure complex human behavior. Behavioral tests used in research today (tests regarding activity, memory, anxiety, stress response, addiction, etc…) are  closely related to the type of animal being used (or the strain used for the species in question). Tests designed for rats and mice there differ frequently, as mice are by nature more mobile and interested in exploring than rats, whereas rats are generally more competent in procedures.

The HAMLET TEST concept is based on getting the animal accustomed to a complex, enriched environment, and on learning. Based on a prototype implemented in the laboratory, this device will make it possible to collect numerous types of information automatically (including movement, eating habits, drinking, physical activity, etc.).

Benefits
Being able to measure behavior is of key importance for developing new treatments for patients suffering from psychiatric disorders and neurodegenerative pathologies.

Applications
Neurodegenerative diseases, behavioral analysis