Joint filler biomaterials

SAYENS



23 Février 2016

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Fields

Chemistry Engineering Biology / Medical

Sectors

Health

 

Presentation

This new biomaterial is made of  sodium alginate. Different layers are deposited on an inert or functionalized medium thanks to aerographic stylets and  a compressor. The alginate solution can be enriched with eukaryote cells or can be associated with other molecules (hyaluronic acid, chondroïtine sulfate). 

The originality resides in initiating reticulation of the sodium alginate solution by adding a defined quantity of calcium chloride solution. The obtained reaction allows the deposition of successive layers, interacting with one another, which enables obtaining an increased material thickness, and therefore, the treatment of deeper lesions.

Competitive advantages

  • Easily adaptable to the dimension of the lesion to fill;
  • Perfect integration to the target zone (good mechanical and biological properties, modular composition);
  • Possibility to increase the joint filler thickness (deposition of successive layers).

Applications/Markets

  • Treatment of focal lesion of joint cartilage;
  • Reconstruction tissue engineering de reconstruction (skin, urothelial vesical epithelium).

Intellectual Property

Patent FR 1153563

Laboratory

Laboratoire en Ingénierie Moléculaire et Physiopathologie Articulaire (IMOPA)

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