The global cosmetics market estimated at 203 billion € in 2015 is growing steadily.
The prohibition of parabens in cosmetics has increased interest for natural preservatives.
A French laboratory with internationally recognized expertise in characterization of natural compounds synthesized new biocidal active ingredients.
These compounds are a new family of alkaloids derived from viscosaline, a natural 3-alkylpyridinium salt produced by sea sponges.
Antimicrobial activity tests:
• These compounds demonstrate anti-adhesion activities against yeast (i.e. Candida albicans), fungi (i.e. Aspergillus brasiliensis) and terrestrial bacteria (i.e. Staphylococcus aureus)
• Activity up to activity up to 99,99% at 0,1 mg/mL ; MIC (Minimum Inhibitory Concentration) up to 0,01 mg/mL
Phenoloxidase test: activity of skin lightening (MIC 0,8 – 1,8 µg/mL)
Viscosaline is very difficult to synthetize and show low biocide activity
Our bio-inspired compounds have many advantages:
• A dual activity: skin lightening and natural preservatives
• An easy and efficient chemical synthesis with eco-compatible natural building blocks
• Specifically inhibit high-risk pathogenic microbial strains causing skin or eye infections in topical cosmetics
• Broad-spectrum anti-adhesion activity: fungi, yeast, marine and terrestrial bacteria, and microalgae
• Biodegradable: potential very low impact on the environment
• Potential weak toxicity
• Natural preservatives
• Skin lightening creams