Peptide activating macrophages
19 Octobre 2017
Fields
Biology / Medical
Sectors
Health
DESCRIPTION
- Naturally occurring recombinant peptide:
- Able to activate macrophage’s cytotoxic functions against pathogens recognized by type C lectin receptors (bacteria, fungi, yeast, parasites) and tumor cells
- Enabling the production of pro-inflammatory cytokines
- Specific activation of macrophages at the tumor site
- Displaying no direct microbicide activity
- Depicting no evident cytotoxicity (on human erythrocytes and monocytes)
- In vitro and in vivo efficacy data on murine model of Candida albicans
- In vitro efficacy data on lymphoma model and colon cancer cells
APPLICATIONS
- Anti-tumor agent
- Anti-infectious agent: bacteria, fungi, yeast, parasites
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