Peptide activating macrophages

TOULOUSE TECH TRANSFER



19 Octobre 2017

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Fields

Biology / Medical

Sectors

Health

DESCRIPTION

  • Naturally occurring recombinant peptide:
    • Able to activate macrophage’s cytotoxic functions against pathogens recognized by type C lectin receptors (bacteria, fungi, yeast, parasites) and tumor cells
    • Enabling the production of pro-inflammatory cytokines
    • Specific activation of macrophages at the tumor site
    • Displaying no direct microbicide activity
    • Depicting no evident cytotoxicity (on human erythrocytes and monocytes)
  • In vitro and in vivo efficacy data on murine model of Candida albicans
  • In vitro efficacy data on lymphoma model and colon cancer cells

 

APPLICATIONS

  • Anti-tumor agent
  • Anti-infectious agent: bacteria, fungi, yeast, parasites
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