SEQONE PROJECT - Next-Generation Genome Screening (NGS) sector

AXLR



14 Mars 2017

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Fields

NICT Biology / Medical

Sectors

NICT
Health

The recent emergence of next-generation of sequencing (NGS), referred to also as “high-throughput screening”, is revolutionizing cellular and molecular biology. The cost of sequencing has become increasingly affordable, and the skyrocketing increase in the production capacity of technical equipment makes it possible to sequence entire genomes in just a few days. Among other benefits, this opens the door to personalized medicine. For example, it is now possible to sequence all of the information contained in a patient’s cancer cells to search for molecular markers that could be used to establish a diagnosis and prognosis, as well as to track residual disease and the patient’s response to treatment.

Benefits
Sequencing data does not produce biological results directly. Raw data is completely unorganized, as if split into a crossword puzzle with a million words. Biologists and clinical practitioners are thus confronted by a flood of data (Big Data) that needs to be stored, structured, and analyzed. The data is unusable in its initial state. Bio-informatics analysis is therefore necessary to bridge the gap between a sequencer’s readings and a sample’s biological meaning. Current solutions remain relatively unsatisfactory. Clinical practitioners and biologists actually have a need to stay independent, and to be able to observe, understand, share, and annotate bio-informatics analysis to focus on specific biological and medical issues.  CORTECT seeks to meet these needs by providing computer tools that offer effective access to data analysis.

Applications
Next-Generation Genome Screening (NGS) sector

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