State-of-the-art platform for fighting against infectious diseases

TOULOUSE TECH TRANSFER



03 Novembre 2015

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Fields

Biology / Medical

Sectors

Health

DESCRIPTION

  • High-standard, high-security animal (BSL3) facilities for mice housing (235 cages)
  • Facilities suited for experimental animal infection, anesthesia, microsurgery, histopathology of infected tissues functional or phenotypic analysis, culture of euka/prokaryotic cells
  • State-of-the-art imaging equipment within BSL3 facilities for monitoring physiological parameters and functional exploration of the immune and pathogen response:
    - Multiparametric flow cytometry and cell sorting systems
    - Live microscopy at the cellular (spinning disk microscope) and whole organ levels (multiphoton microscopy)
    - Thin sections of live infected tissues (vibratome technique)
  • Types of provided services:
    - Pay-for-use: customer has a full access to the facility
    - All inclusive: platform runs the experiments based on customer’s full specifications
    - Top-up expertise: specific advice on any part of the study
 

APPLICATIONS

  • Test of vaccine or drug efficacy against BSL2 & BSL3 pathogens in vivo
  • Determination of the phenotype and functions of cell populations (prokaryotic & eukaryotic) directly harvested from infected or vaccinated animals, without the need for chemical/physical inactivation
  • Histopathology
  • Live imaging of infected cells and tissues
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