Analytes detection (e.g. proteins, nucleic acids, DNA, bacterial fragments…) is important for both molecular biology research and medical applications.
However, the existing detection methods show a low signal to noise ratio, that results in a limited sensitivity and a low specificity.
2C-DLS is an original method and system for detection the presence of analytes in solution, with an excellent signal to noise ration and a very good specificity.
HOW IT WORKS
The method takes advantage of using two different nano-probes, used to bound to one targeted analyte.
As each probe has a specific optical response, the method enables to specifically detect the aggregate formed by the analyte combined with, at least, first and second probes.
When light scattered by the probes are detected simultaneously over time, it confirms the presence of the analyte in the solution.
KEY BENEFITS vs. STATE OF THE ART
Detection and analysis of biomolecules: DNA, proteins, bacterial fragments…