Nanofluidic platform for on-chip real-time binding kinetic assays

TOULOUSE TECH TRANSFER



01 Mars 2016

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Fields

Chemistry Engineering Biology / Medical

Sectors

Chemicals, Materials & Plant-based Materials
Measurement & Instrumentation
Health

DESCRIPTION

  • Nanofluidic platform for kinetic assays:
    - Interaction of injected fluorescent analytes with probe molecules grafted in nanoslit with high capture efficiency
    - Real-time molecular kinetics studied by fluorescence imaging
    - Fluorescent detection compatible with standard wide field microscope
    - Multi-concentration screening possibility in a single experiment with access to on/off kinetic data
    - Fluid actuation by simple pressure source, chip regeneration and multi-usage possible 

 

APPLICATIONS

• Characterization of biomolecular interaction in:
- Fundamental life-science studies
- Drug screening
- Immunogenicity test
- Companion test

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