Context: Despite their efficiency, chemotherapy treatments are being challenged by physicians regarding their strong side-effects when they are administrated in systemic way. Numerous devices have been designed to deliver the treatment in situ hence reducing side-effects.
Issue: Due to implantation’s site (inside the vessels for some), their design or the lack of delivery management, they cause other side effects including thrombosis or surgery complication. So there is still a need to develop a device which is able to deliver in situ the treatment and prevent cancer relapse.
Solution: Thank to its expertise in both microfluidic and biological field, the research team has developed a new implantable medical device which could be used to deliver therapeutics directly inside the tumor or around it while avoiding surgery complication and reducing side-effects eventually.
Dose delivery control
To be used with different kind of molecules (cytotoxic agent, siRNA, Protein or antibody)
Less side-effect expected
Easy to manage the dose escalation by chronic or intermittent injections
Glioblastoma after resection to enhance Stupp protocole
Hepato-carcinoma and metastasis in late stage and in first or second line treatment for non-resecable tumor
Stade de développement
TRL3 - Recherche de la preuve de concept
Laboratoire de recherche
UMR_S 1066 - MINT
Équipe de recherche
Conception de Micro et Nanomédecines
Propriété intellectuelle associée
FR : FR1656954 - filed on the 07-21-2016
WO - CA,CN,EP,JP,US