OLIGONUCLEOTID TABLETS: Process to formulate oligonucleotids into tablets for an oral administration

AQUITAINE SCIENCE TRANSFERT



27 Février 2018

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Fields

Biology / Medical

Sectors

Health

APPLICATIONS

  • New galenic formulation for therapeutic approach based on oligonucleotids
  • Tablets suitable for siRNA, shRNA, miRNA, mRNA and RNAi
  • Oral administration of biological active molecules

DESCRIPTION

  • Patented process to compress into tablets the oligonucleotids while maintaining their therapeutic activity
  • Compatible with large panel of encapsulated vectors
  • Possibility to combine the approach with the well known process to control the delivery
  • Combination of multiple therapeutic oligonucleotids in a single tablet

BENEFITS

  • Opens new perspectives for simple use of therapeutic oligonucleotids
  • Obtention of sterilized, stable, easy to store tablets
  • High patient compliance expected
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