QUANTI-HLAb: An In Vitro Diagnostic Kit for transplant recipients

AQUITAINE SCIENCE TRANSFERT



27 Février 2018

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Fields

Biology / Medical

Sectors

Measurement & Instrumentation
Health

APPLICATIONS

  • Diagnostic kit for organ transplantation
  • Identification of HLA antibodies parameters
  • Evaluation of HLA antibodies pathogenicity
  • Prevention of transplant rejection
  • Follow-up of humoral rejection therapies

DESCRIPTION

  • Innovative technology based on Surface Plasmon Resonance (SPR) in a capture mode,
  • Access to HLA antibodies’ active concentration and affinity,
  • Active concentration (high capture level) and affinity (low capture level) of several sample/HLA targets can be performed on the same chip.

BENEFITS

  • Determination of quantitative parameters for HLA antibodies in patient samples
  • No calibration curve and reusable chip
  • Real-time and label-free assay
  • To anticipate clinical outcomes for organ recipients
  • To facilitate clinical decision

IP

This technology is protected by a patent application

MATURATION

Proof of concept established on a cohort of lung transplant recipients

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