Fields
Biology / MedicalSectors
Health
Dive technology consist in a dopaminergic stimulation by continuous intra-cerebro ventricular delivery of anaerobic dopamine, in the third ventricle, closed to the target of the nigro-striatal system in Parkinson's disease at the stage of motor fluctuations:
The preclinical data displayed a huge symptomatic effect in MPTP mouse and 6 OH rat models without dyskinesia and a large therapeutic index as compared with
peripheral administration of L-dopa.
A neuroprotection of the dopaminergic neurons has been obtained within the substantia nigra and the striatum in the MPTP mouse model
Benefits: